A 24- to 26-hour zebrafish embryo (~2 millimeters long) whose left forebrain has been transformed into a section of the hindbrain, as indicated by the ectopic expression of a hindbrain-specific RNA marker (blue), in place of the eye. This posterior transformation of the cells is caused by a patterning signal from nonaxial mesendodermal precursor cells transplanted to the presumptive forebrain region at the shield stage. See page 254. [Image: K. Woo and S. E. Fraser]

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