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Colony of Candida albicans carrying a deletion of the TUP1 gene. This pathogenic yeast normally switches between single-cell and filamentous states, and both forms are found in its infected mammalian hosts. The tup1 deletion mutant strain grows exclusively as filaments, as seen here on a plate of low-nutrient medium (the width of the field is ~200 micrometers). See page 105 and the related Perspective on page 52. [Image: Burkhard R. Braun and Alexander D. Johnson]

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Science. ISSN 0036-8075 (print), 1095-9203 (online)