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Ultrahigh-resolution images of a rabbit trachea (~6 mm diameter) obtained in vivo by catheter-endoscope-based optical coherence tomography. The technique probes the tissue with light from a fiber optic source by collecting photons reflected from features in the wall. It is one of the imaging technologies transforming fields including medical diagnosis, cell biology, and materials science. See page 2037, the special News section (page 1981), and links to related items. [Image: C. Pitris, G. Tearney, B. Bouma, S. Boppart, J. Fujimoto, M. Brezinski]

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Science. ISSN 0036-8075 (print), 1095-9203 (online)