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About the Cover


A cluster of the sea star Pisaster ochraceus on a beach of the Pacific Rim National Park, Vancouver Island, British Columbia. The oocytes from this echinoderm have been used as a source of the mitogen-activated protein (MAP) kinase p44mpk, which is now shown to be phosphorylated and activated by the lymphocyte protein tyrosine kinase p56lck. See page 853. [Photograph by Peter Thomas]


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Science. ISSN 0036-8075 (print), 1095-9203 (online)