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Living nonadherent P388D1 cells (from murine lymphoid neoplasm), stained here with a red fluorescent dye, are retained in wells (50 {mu}m square and 50 {mu}m deep) etched into the surface of a potentiometric silicon biosensor. The sensor measures metabolic rates, which are affected by a variety of biological and chemical agents. See page 243. [Photograph by J. C. Owicki and K. M. Kercso, Molecular Devices Corporation, Menlo Park, CA 94025]


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Science. ISSN 0036-8075 (print), 1095-9203 (online)