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Eppendorf & Science Prize for Neurobiology

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Science 21 March 2008:
Vol. 319. no. 5870, p. 1612
DOI: 10.1126/science.319.5870.1612
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News Focus

STRUCTURAL BIOLOGY:
Researchers Hone Their Homology Tools

Robert F. Service

How well do homology models, which use solved structures as templates for computer models of the three-dimensional shapes of closely related proteins, work? Not well enough, according to members of a review panel that issued a mixed report card on the Protein Structure Initiative in December.

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