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Science 7 February 2003:
Vol. 299. no. 5608, pp. 849 - 852
DOI: 10.1126/science.299.5608.849
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News

Obesity Drug Pipeline Not So Fat

Trisha Gura

Why aren't there more antiobesity drugs? For one, such drugs must tamper with the biochemistry of metabolism; it's an essential system for survival and thus sometimes fatal to disrupt. In addition, appetite circuits in the brain use neurotransmitters and receptors that control other body processes. And yet research is beginning to yield important insights into the body's cast of caloric characters (see p. 846).

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Obesity and the Neuroendocrine Control of Energy Homeostasis: The Role of Spontaneous Locomotor Activity.
T. R. Castaneda, H. Jurgens, P. Wiedmer, P. Pfluger, S. Diano, T. L. Horvath, M. Tang-Christensen, and M. H. Tschop (2005)
J. Nutr. 135, 1314-1319
   Abstract »    Full Text »    PDF »
Pharmacological Therapy of Obesity: Past, Present, and Future.
D. S. Weigle (2003)
J. Clin. Endocrinol. Metab. 88, 2462-2469
   Full Text »    PDF »
An Update on the Obesity Problem.
(2003)
Journal Watch (General) 2003, 8
   Full Text »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)