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Science 20 December 2002:
Vol. 298. no. 5602, pp. 2342 - 2343
DOI: 10.1126/science.1080373

Perspectives

HUMAN GENETICS:
Mapping Human History

Mary-Claire King and Arno G. Motulsky

Analyzing genetic markers in the DNA of individuals from different parts of the world can reveal the migrations of our ancestors. In their Perspective, King and Motulsky discuss a new statistical analysis that-without using prior information about individuals' origins-identifies genetic clusters corresponding to five major geographic regions of the world (Rosenberg et al.). The same analysis confirms that more than 90% of human genetic variation is within populations rather than among groups.


The authors are in the Department of Medicine (Medical Genetics) and Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA. E-mail: mcking{at}u.washington.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)