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Science 2 August 2002:
Vol. 297. no. 5582, pp. 781 - 783
DOI: 10.1126/science.1075454
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Perspectives

DEVELOPMENT:
Riding the Crest of the Wnt Signaling Wave

Paul Trainor and Robb Krumlauf

Formation of the neural crest is a crucial step during the embryonic development of vertebrates, but the signals that direct neural crest induction are largely unknown. In their Perspective, Trainor and Krumlauf discuss new findings (García-Castro et al.) revealing that Wnt6 expression in the surface ectoderm directs neural crest induction.

The authors are at the Stowers Institute for Medical Research, Kansas City, MO 64110, USA. E-mail: rek{at}stowers-institute.org, pat{at}stowers-institute.org

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