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Science 5 October 2001:
Vol. 294. no. 5540, pp. 30 - 31
DOI: 10.1126/science.294.5540.30
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News of the Week

GENETICS:
Closing In on the Centromere

Elizabeth Pennisi

On page 109, geneticists provide the clearest look yet at a human centromere, the cinched waist of a chromosome. They have demonstrated that a 3-million-base stretch of DNA embedded in what many have called the centromere is really all it takes to make a functional centromere. To their surprise, the nature of this core DNA indicates that, rather than being highly conserved, the centromere has changed significantly during primate evolution.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)