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Science 17 August 2001:
Vol. 293. no. 5533, pp. 1270 - 1271
DOI: 10.1126/science.1062504
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Perspectives

BIOCHEMISTRY:
TRP Ion Channels--Two Proteins in One

Irwin B. Levitan and Susan M. Cibulsky

It is well established that some proteins carry out more than one job in the cell, but so far, ion channels do not appear to exhibit this versatility. In their Perspective, Levitan and Cibulsky discuss a cluster of new findings showing that two members of the long TRP ion channel family, LTRPC7 and LTRPC2, are both ion channels and enzymes.

The authors are in the Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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