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Science 16 March 2001:
Vol. 291. no. 5511, pp. 2099 - 2101
DOI: 10.1126/science.1060125
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Perspectives

DEVELOPMENT:
How to Stimulate Your Partner

Anne M. Villeneuve

The cytoskeletal protein major sperm (MSP) of nematode sperm is required for these amoeboid cells to move in search of oocytes. As Villeneuve explains in her Perspective, it now turns out that MSP, when released by sperm, behaves as a bipartite signaling molecule that can both induce oocytes to mature and stimulate ovulation by causing gonad sheath cells to contract (Miller et al.).

The author is in the Departments of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. E-mail: villen{at}cmgm.stanford.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
An Eph receptor sperm-sensing control mechanism for oocyte meiotic maturation in Caenorhabditis elegans.
M. A. Miller, P. J. Ruest, M. Kosinski, S. K. Hanks, and D. Greenstein (2003)
Genes & Dev. 17, 187-200
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