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Science 8 December 2000:
Vol. 290. no. 5498, pp. 1904 - 1905
DOI: 10.1126/science.290.5498.1904

Perspectives

Also see the archival list of Science's Compass: Enhanced Perspectives

DEVELOPMENT:
Enhanced: Hear, Hear, for the Inner Ear

Anthony Graham

Although the development of the inner ear has been a favorite subject for biologists to study, it is not yet clear exactly which molecules are involved in the induction of the otic placode, the plug of embryonic ectoderm that will become the inner ear. In his Perspective, Graham takes us on an inner ear odyssey, explaining how the signaling molecules FGF-19 and Wnt-8c cooperate to induce formation of the otic placode (Ladher et al.).


The author is at the MRC Centre for Developmental Neurobiology, Kings College London, London SE1 1UL, UK. E-mail: anthony.graham{at}kcl.ac.uk

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Science. ISSN 0036-8075 (print), 1095-9203 (online)