Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Bone repair may be one of the first major applications of tissue engineering; efforts to encourage the growth of new bone using novel matrices, bone morphogenic proteins, gene therapy, and stem cells are all showing promise. But the commercial stakes are so high that some researchers are worried that patent claims, and a reluctance to test competing technologies in combination, could delay progress in the field.
The editors suggest the following Related Resources on Science sites:
In Science Magazine
INTRODUCTION TO SPECIAL ISSUE
Paula Kiberstis, Orla Smith, and Colin Norman (1 September 2000) Science289 (5484), 1497.
[DOI: 10.1126/science.289.5484.1497] |Summary »
REVIEW
Patricia Ducy, Thorsten Schinke, and Gerard Karsenty (1 September 2000) Science289 (5484), 1501.
[DOI: 10.1126/science.289.5484.1501] |Abstract »|Full Text »|PDF »
REVIEW
Steven L. Teitelbaum (1 September 2000) Science289 (5484), 1504.
[DOI: 10.1126/science.289.5484.1504] |Abstract »|Full Text »|PDF »
REVIEW
Gideon A. Rodan and T. John Martin (1 September 2000) Science289 (5484), 1508.
[DOI: 10.1126/science.289.5484.1508] |Abstract »|Full Text »|PDF »
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
In Vitro Angiogenesis of 3D Tissue Engineered Adipose Tissue.
Rui Yao, Renji Zhang, Yongnian Yan, and Xiaohong Wang (2009)
Journal of Bioactive and Compatible Polymers
24, 5-24
|Abstract »|PDF »
Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goats.
T. T. Tang, B. Lu, B. Yue, X. H. Xie, Y. Z. Xie, K. R. Dai, J. X. Lu, and J. R. Lou (2007)
J Bone Joint Surg Br
89-B, 127-129
|Abstract »|Full Text »|PDF »
Tissue Engineering Special Feature: In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation.
N. Datta, Q. P. Pham, U. Sharma, V. I. Sikavitsas, J. A. Jansen, and A. G. Mikos (2006)
PNAS
103, 2488-2493
|Abstract »|Full Text »|PDF »
Osteoblasts Adherence and Migration through Three-dimensional Porous Mineralized Collagen Based Composite: nHAC/PLA.
S. S. Liao, F. Z. Cui, and Y. Zhu (2004)
Journal of Bioactive and Compatible Polymers
19, 117-130
|Abstract »|PDF »
Regulation of BMP-Induced Transcription in Cultured Human Bone Marrow Stromal Cells.
D. L. Diefenderfer, A. M. Osyczka, J. P. Garino, and P. S. Leboy (2003)
J. Bone Joint Surg. Am.
85, 19-28
|Abstract »|Full Text »|PDF »
Expression and Activation of the BMP-Signaling Components in Human Fracture Nonunions.
P. Kloen, S. B. Doty, E. Gordon, I. F. Rubel, M.-J. Goumans, and D. L. Helfet (2002)
J. Bone Joint Surg. Am.
84, 1909-1918
|Abstract »|Full Text »|PDF »
What's New in Musculoskeletal Tumor Surgery.
M. C. Gebhardt (2001)
J. Bone Joint Surg. Am.
83, 629
|Full Text »
Multiple Myeloma: New Insights and Therapeutic Approaches.
K. C. Anderson, R. A. Kyle, W. S. Dalton, T. Landowski, K. Shain, R. Jove, L. Hazlehurst, and J. Berenson (2000)
Hematology
2000, 147-165
|Abstract »|Full Text »|PDF »