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Science 30 January 2009:
Vol. 323. no. 5914, pp. 593 - 594
DOI: 10.1126/science.1169555
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Perspectives

BIOCHEMISTRY:
Unfolding the Secrets of Calmodulin

Robert B. Best,1 Gerhard Hummer2

Researchers have now observed in real time how a single molecule of calmodulin refolds and how it binds to a ligand.

1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.

2Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD 20892, USA. E-mail: gerhard.hummer{at}nih.gov

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Science. ISSN 0036-8075 (print), 1095-9203 (online)