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Science 30 January 2009:
Vol. 323. no. 5914, pp. 588 - 589
DOI: 10.1126/science.1169414
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Perspectives

CELL BIOLOGY:
The Force Is with Us

Martin A. Schwartz

Through changes in protein conformation and interactions, cells sense and respond to forces at their point of attachment to extracellular matrix.

Departments of Microbiology, Cell Biology, and Biomedical Engineering, Cardiovascular Research Center and Mellon Urological Cancer Research Institute, University of Virginia, Charlottesville, VA 22908, USA. E-mail: maschwartz{at}virginia.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)