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Science 7 November 2008:
Vol. 322. no. 5903, pp. 861 - 862
DOI: 10.1126/science.1167363
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Policy Forum

GENETICS:
The Human Variome Project

Richard G. H. Cotton,1,2,3* Arleen D. Auerbach,1 Myles Axton,1 Carol Isaacson Barash,1 Samuel F. Berkovic,4 Anthony J. Brookes,1 John Burn,1 Garry Cutting,1 Johan T. den Dunnen,1 Paul Flicek,1 Nelson Freimer,5 Marc S. Greenblatt,1 Heather J. Howard,2 Michael Katz,1 Finlay A. Macrae,1 Donna Maglott,1 Gabriela Möslein,1 Sue Povey,1 Rajkumar S. Ramesar,1 Carolyn S. Richards,1 Daniela Seminara,1 Timothy D. Smith,2 María-Jesús Sobrido,6 Jan Helge Solbakk,1 Rudolph E. Tanzi,7 Sean V. Tavtigian,1 Graham R. Taylor,1 Joji Utsunomiya,1 Michael Watson,3

An ambitious plan to collect, curate, and make accessible information on genetic variations affecting human health is beginning to be realized.

1Discussion leaders for the Human Variome Project Planning Meeting 2008.

2Genomic Disorders Research Centre, Howard Florey Institute, Melbourne, Australia.

3Cochair of the HVP Planning Meeting.

4Epilepsy Research Centre.

4University of Melbourne, Austin Health West Heidelberg, Australia.

5UCLA Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA.

5Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain, and Center for Network Biomedical Research on Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain.

7Harvard Medical School & Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, MA, USA. Complete affiliations are listed in the supporting online material.

*Author for correspondence. E-mail: cotton{at}unimelb.edu.au

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Science. ISSN 0036-8075 (print), 1095-9203 (online)