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Science 19 September 2008:
Vol. 321. no. 5896, pp. 1644 - 1645
DOI: 10.1126/science.1164586

Perspectives

MICROBIOLOGY:
Desperately Seeking New Antibiotics

David J. Payne

New approaches for discovering the next generation of antibiotics are needed to combat the rise in bacteria that are resistant to current drugs.


Antibacterial Disease Performance Unit, Infectious Diseases Center of Excellence, GlaxoSmithKline, Collegeville, PA 19426, USA. E-mail: david.j.payne{at}gsk.com

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
M.-T. Sung, Y.-T. Lai, C.-Y. Huang, L.-Y. Chou, H.-W. Shih, W.-C. Cheng, C.-H. Wong, and C. Ma (2009)
PNAS 106, 8824-8829
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A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore.
J. R. Miller, S. Dunham, I. Mochalkin, C. Banotai, M. Bowman, S. Buist, B. Dunkle, D. Hanna, H. J. Harwood, M. D. Huband, et al. (2009)
PNAS 106, 1737-1742
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