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Science 1 August 2008:
Vol. 321. no. 5889, pp. 648 - 649
DOI: 10.1126/science.1162212
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Perspectives

CELL SIGNALING:
"Make and Brake" in Signaling

Aristides G. Eliopoulos

Proteolysis of one component of a receptor-bound complex releases the complex from the cell surface to the cytoplasm to activate kinase signaling.

The University of Crete Medical School and Institute for Molecular Biology and Biotechnology, Foundation of Research and Technology Hellas, Heraklion, Greece. E-mail: eliopag{at}med.uoc.gr

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Science. ISSN 0036-8075 (print), 1095-9203 (online)