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Science 25 July 2008:
Vol. 321. no. 5888, pp. 499 - 500
DOI: 10.1126/science.1162125
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Perspectives

BIOCHEMISTRY:
Cargo Load Reduction

Ineke Braakman and Mieko Otsu

A specific enzyme that reduces protein disulfide bonds is part of a complex that eliminates aggregated, misfolded proteins.

Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Faculty of Science, Utrecht University, Utrecht 3584 CH, Netherlands. E-mail: i.braakman{at}uu.nl

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Science. ISSN 0036-8075 (print), 1095-9203 (online)