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Science 30 May 2008:
Vol. 320. no. 5880, pp. 1168 - 1169
DOI: 10.1126/science.1159090
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Perspectives

IMMUNOLOGY:
Immunity Benefits from a Little Suppression

George Kassiotis1 and Anne O'Garra2

Regulatory T cells thought to limit the extent of an inflammatory response to viral infection can actually optimize the response by redirecting it to sites of infection.

1Division of Immunoregulation, MRC National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK. E-mail: gkassio{at}nimr.mrc.ac.uk

2Division of Immunoregulation, MRC National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK. E-mail: aogarra{at}nimr.mrc.ac.uk

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Science. ISSN 0036-8075 (print), 1095-9203 (online)