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Science 23 May 2008:
Vol. 320. no. 5879, pp. 1019 - 1020
DOI: 10.1126/science.1159246
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Perspectives

BIOCHEMISTRY:
SNO Removal

Arne Holmgren

Reduced thioredoxin denitrosylates caspase-3, a key protein involved in cell death.

Medical Nobel Institute for Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden. E-mail: arne.holmgren{at}ki.se

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation.
R. Luan, S. Liu, T. Yin, W. B. Lau, Q. Wang, W. Guo, H. Wang, and L. Tao (2009)
Cardiovasc Res 83, 294-302
   Abstract »    Full Text »    PDF »
Regulation of the Catalytic Activity and Structure of Human Thioredoxin 1 via Oxidation and S-Nitrosylation of Cysteine Residues.
S. I. Hashemy and A. Holmgren (2008)
J. Biol. Chem. 283, 21890-21898
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)