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Science 1 February 2008:
Vol. 319. no. 5863, pp. 578 - 579
DOI: 10.1126/science.1154253

Perspectives

MOLECULAR BIOLOGY:
The Art of Assembly

Francis Szoka

Advances in delivering small interfering RNAs to specific tissues may bring these nucleotides closer to reality as therapeutic agents.


The author is in the Department of Biopharmaceutical Sciences and Pharmaceutical Chemistry, University of California, San Francisco, CA 94143-0446, USA. E-mail: szoka{at}cgl.ucsf.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Targeting Melanoma Growth and Metastasis with Systemic Delivery of Liposome-Incorporated Protease-Activated Receptor-1 Small Interfering RNA.
G. J. Villares, M. Zigler, H. Wang, V. O. Melnikova, H. Wu, R. Friedman, M. C. Leslie, P. E. Vivas-Mejia, G. Lopez-Berestein, A. K. Sood, et al. (2008)
Cancer Res. 68, 9078-9086
   Abstract »    Full Text »    PDF »
Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.
R. Juliano, Md. R. Alam, V. Dixit, and H. Kang (2008)
Nucleic Acids Res. 36, 4158-4171
   Abstract »    Full Text »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)