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Science 11 January 2008:
Vol. 319. no. 5860, pp. 164 - 165
DOI: 10.1126/science.1153713
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Perspectives

CANCER:
Quo Vadis, Specificity?

Hans Schreiber and Donald A. Rowley

Mutations in cancer cells can give rise to tumor-specific antigens, but abnormal processing of normal molecules in these cells can also elicit an immune response.

The authors are in the Department of Pathology, University of Chicago, Chicago, IL 60637, USA. E-mail: hszz{at}midway.uchicago.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)