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The ability to generate pluripotent stem cells directly from skin fibroblasts may render ethical debates over the use of human oocytes to create stem cells irrelevant.
The author is in the Departments of Animal Sciences and Physiology, Cellular Reprogramming Laboratory, Michigan State University, East Lansing, MI 48824, USA, and at the Program for Cell Therapy and Regenerative Medicine of Andalusia, Seville, Spain. E-mail: cibelli{at}msu.edu
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