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Science 16 November 2007:
Vol. 318. no. 5853, pp. 1077 - 1078
DOI: 10.1126/science.1150705

Perspectives

GENETICS:
Widespread Monoallelic Expression

Rolf Ohlsson

The surprisingly high prevalence of random allele inactivation in human cells can generate diversity in gene expression that affects cell fate and physiology.


The author is in the Department of Development and Genetics, Uppsala University, Norbyvägen 18A, S-752 36 Uppsala, Sweden. E-mail: rolf.ohlsson{at}ebc.uu.se

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Nonallelic transvection of multiple imprinted loci is organized by the H19 imprinting control region during germline development.
K. S. Sandhu, C. Shi, M. Sjolinder, Z. Zhao, A. Gondor, L. Liu, V. K. Tiwari, S. Guibert, L. Emilsson, M. P. Imreh, et al. (2009)
Genes & Dev. 23, 2598-2603
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Science. ISSN 0036-8075 (print), 1095-9203 (online)