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Science 14 September 2007:
Vol. 317. no. 5844, pp. 1507 - 1508
DOI: 10.1126/science.1148905
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Perspectives

IMMUNOLOGY:
Square-Dancing Antibodies

Dennis R. Burton and Ian A. Wilson

Antibody therapies need to take account of a subclass of immunoglobulin G that can swap subunits in vivo.

D. R. Burton is in the Departments of Immunology and Molecular Biology, and I. A. Wilson is in the Department of Molecular Biology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. E-mail: burton{at}scripps.edu, wilson{at}scripps.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)