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Science 22 June 2007:
Vol. 316. no. 5832, pp. 1710 - 1711
DOI: 10.1126/science.1145014
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Perspectives

CELL SIGNALING:
Nuclear Actin as Choreographer of Cell Morphology and Transcription

Jiang I. Wu and Gerald R. Crabtree*

Changes in the cell's cytoskeleton affect gene expression through a signaling circuit that involves regulation of cofactor transport and function by actin in the nucleus.

The authors are at Howared Hughes Medical Institute and Stanford University School of Medicine, Stanford, CA 94305-5323, USA. E-mail: crabtree{at}cmgm.stanford.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Sequences in Intron 51 of the von Willebrand Factor Gene Target Promoter Activation to a Subset of Lung Endothelial Cells in Transgenic Mice.
A. M. Kleinschmidt, M. Nassiri, M. S. Stitt, K. Wasserloos, S. C. Watkins, B. R. Pitt, and N. Jahroudi (2008)
J. Biol. Chem. 283, 2741-2750
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Science. ISSN 0036-8075 (print), 1095-9203 (online)