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Science 18 May 2007:
Vol. 316. no. 5827, pp. 988 - 989
DOI: 10.1126/science.1143337
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Perspectives

CANCER:
Converging on beta-Catenin in Wilms Tumor

Roel Nusse

A common thread in some cancers is mutations in a developmental signaling pathway that ultimately affect the action of a single component.

The author is in the Department of Developmental Biology, Howard Hughes Medical Institute, Stanford University, School of Medicine, Stanford, CA 94305-5323, USA. E-mail: rnusse{at}stanford.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
An integrated genome screen identifies the Wnt signaling pathway as a major target of WT1.
M. K.-H. Kim, T. J. McGarry, P. O Broin, J. M. Flatow, A. A.-J. Golden, and J. D. Licht (2009)
PNAS 106, 11154-11159
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Science. ISSN 0036-8075 (print), 1095-9203 (online)