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Science 23 March 2007:
Vol. 315. no. 5819, pp. 1673 - 1674
DOI: 10.1126/science.1141184
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Perspectives

IMMUNOLOGY:
Asymmetry and Immune Memory

Dan R. Littman1 and Harinder Singh2

Asymmetric cell division of lymphocytes ensures that our adaptive immune system maintains a balanced production of two different types of T cells.

1D. R. Littman is in the Howard Hughes Medical Institute, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA. E-mail: littman{at}saturn.med.nyu.edu

2H. Singh is in the Howard Hughes Medical Institute, Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA. E-mail: hsingh{at}uchicago.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse.
R. A. Maldonado, M. A. Soriano, L. C. Perdomo, K. Sigrist, D. J. Irvine, T. Decker, and L. H. Glimcher (2009)
J. Exp. Med. 206, 877-892
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Science. ISSN 0036-8075 (print), 1095-9203 (online)