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Science 22 December 2006:
Vol. 314. no. 5807, pp. 1884 - 1886
DOI: 10.1126/science.1137300
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Perspectives

EPIDEMIOLOGY:
Influenza Escapes Immunity Along Neutral Networks

Erik van Nimwegen

Given that influenza virus continues to escape immunity, why is it that only one strain dominates each year? The answer may lie in neutral networks and mapping viral genotypes to antigenic phenotypes.

The author is in the Division of Bioinformatics, Biozentrum, University of Basel, 4056 Basel, Switzerland. E-mail: erik.vannimwegen{at}unibas.ch

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Genetic and Epidemiological Analysis of Influenza Virus Epidemics in Taiwan during 2003 to 2006.
J.-W. Jian, G.-W. Chen, C.-T. Lai, L.-C. Hsu, P.-J. Chen, S. H.-S. Kuo, H.-S. Wu, and S.-R. Shih (2008)
J. Clin. Microbiol. 46, 1426-1434
   Abstract »    Full Text »    PDF »
The molecular epidemiology of influenza viruses: a lesson from a highly epidemic season.
P D'Agaro, T Rossi, P Burgnich, G D. Molin, N Coppola, G Rocco, and C Campello (2008)
J. Clin. Pathol. 61, 355-360
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)