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Originally published in Science Express on 9 November 2006
Science 1 December 2006:
Vol. 314. no. 5804, pp. 1402 - 1403
DOI: 10.1126/science.1136314
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Perspectives

CELL BIOLOGY:
Tools to Tamper with Phosphoinositides

Stuart McLaughlin

Rapidly depleting or elevating specific phosphoinositide lipids in the plasma membrane reveals their role in controlling cellular processes.

The author is in the Department of Physiology, Stony Brook University, Stony Brook, NY 11794-8661, USA. E-mail smclaughlin{at}notes.cc.sunysb.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The "Electrostatic-Switch" Mechanism: Monte Carlo Study of MARCKS-Membrane Interaction.
S. Tzlil, D. Murray, and A. Ben-Shaul (2008)
Biophys. J. 95, 1745-1757
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Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion.
J. Liou, M. Fivaz, T. Inoue, and T. Meyer (2007)
PNAS 104, 9301-9306
   Abstract »    Full Text »    PDF »
Membrane-permeable Calmodulin Inhibitors (e.g. W-7/W-13) Bind to Membranes, Changing the Electrostatic Surface Potential: DUAL EFFECT OF W-13 ON EPIDERMAL GROWTH FACTOR RECEPTOR ACTIVATION.
P. Sengupta, M. J. Ruano, F. Tebar, U. Golebiewska, I. Zaitseva, C. Enrich, S. McLaughlin, and A. Villalobo (2007)
J. Biol. Chem. 282, 8474-8486
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Science. ISSN 0036-8075 (print), 1095-9203 (online)