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CANCER: Enhanced: Cancer Immunotherapy Is More Than a Numbers Game
Rienk Offringa
White blood cells that are genetically engineered to destroy human melanoma prove effective for a few patients in a clinical trial. A variety of strategies might increase the success rate.
The author is head of the Tumor Immunology Group, Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands. E-mail: r.offringa{at}lumc.nl
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In Science Magazine
REPORTS
Richard A. Morgan, Mark E. Dudley, John R. Wunderlich, Marybeth S. Hughes, James C. Yang, Richard M. Sherry, Richard E. Royal, Suzanne L. Topalian, Udai S. Kammula, Nicholas P. Restifo, Zhili Zheng, Azam Nahvi, Christiaan R. de Vries, Linda J. Rogers-Freezer, Sharon A. Mavroukakis, and Steven A. Rosenberg (6 October 2006) Science314 (5796), 126.
[DOI: 10.1126/science.1129003] |Abstract »|Full Text »|PDF »|Supporting Online Material »
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