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Science 30 June 2006:
Vol. 312. no. 5782, pp. 1886 - 1887
DOI: 10.1126/science.1130324
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Perspectives

MOLECULAR BIOLOGY:
Enhanced: Accurate RNA Siting and Splicing Gets Help from a DEK-Hand

Tracy L. Kress and Christine Guthrie

Mature messenger RNA is prepared in eukaryotes by splicing together the protein-coding sequences of precursors. A chromatin-associated protein proofreads these splice sites in the RNA, ensuring accuracy.

The authors are in the Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143-0448, USA. E-mail: guthrie{at}biochem.ucsf.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)