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Science 26 May 2006:
Vol. 312. no. 5777, pp. 1160 - 1161
DOI: 10.1126/science.312.5777.1160
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News

Autophagy: Is It Cancer's Friend or Foe?

Jean Marx

Cells rely on autophagy to recycle their components, and much evidence favors the idea that this "self-eating" suppresses tumor development. But other data suggest that autophagy fosters tumor development and actually protects cancer cells from treatments. (Read more.)

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Vitamin D3 Induces Autophagy of Human Myeloid Leukemia Cells.
J. Wang, H. Lian, Y. Zhao, M. A. Kauss, and S. Spindel (2008)
J. Biol. Chem. 283, 25596-25605
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Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both autophagy and apoptotic death in endothelial cells.
T. M. B. Nguyen, I. V. Subramanian, A. Kelekar, and S. Ramakrishnan (2007)
Blood 109, 4793-4802
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Science. ISSN 0036-8075 (print), 1095-9203 (online)