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Science 24 May 2006:
Vol. 312. no. 5777, pp. 1150 - 1151
DOI: 10.1126/science.1128785
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Perspectives

MICROBIOLOGY:
Bacteria Seize Control by Acetylating Host Proteins

Carolyn A. Worby and Jack E. Dixon

The plague-causing bacterium Yersinia pestis injects toxic proteins into its hosts' cells. One of these interferes with the host's secretion of a protective factor by adding acetyl groups to a signaling kinase, blocking its activation.

The authors are in the Departments of Pharmacology, Cellular and Molecular Medicine, and Chemistry and Biochemistry, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. E-mail: jedixon{at}ucsd.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Silencing of Host Cell CYBB Gene Expression by the Nuclear Effector AnkA of the Intracellular Pathogen Anaplasma phagocytophilum.
J. C. Garcia-Garcia, K. E. Rennoll-Bankert, S. Pelly, A. M. Milstone, and J. S. Dumler (2009)
Infect. Immun. 77, 2385-2391
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Science. ISSN 0036-8075 (print), 1095-9203 (online)