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Science 5 May 2006:
Vol. 312. no. 5774, pp. 709 - 710
DOI: 10.1126/science.1127652
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Perspectives

IMMUNOLOGY:
B Cells Spread and Gather

Margaret M. Harnett

Immune cells that produce effective antibodies against foreign proteins are selected by a synapse-like interaction with antigen-presenting cells that promotes the survival of the cells with high-affinity binding.

The author is in the Division of Immunology, Infection and Inflammation, Glasgow Biomedical Research Centre, University of Glasgow, Glasgow G12 8TA, UK. E-mail: M.Harnett{at}bio.gla.ac.uk

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Science. ISSN 0036-8075 (print), 1095-9203 (online)