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Science 28 April 2006:
Vol. 312. no. 5773, pp. 540 - 541
DOI: 10.1126/science.1127236
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Perspectives

NEUROSCIENCE:
A Neuronal Receptor for Botulinum Toxin

Reinhard Jahn

Muscle paralysis induced by botulinum toxin A is used cosmetically to eliminate wrinkles. It preferentially enters activated neurons by binding to a synaptic vesicle protein that becomes exposed after transmitter release.

The author is in the Department of Neurobiology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany. E-mail: rjahn{at}gwdg.d

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