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Science 28 April 2006:
Vol. 312. no. 5773, pp. 537 - 538
DOI: 10.1126/science.1127182
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Perspectives

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EVOLUTION:
Enhanced: Size Does Not Matter for Mitochondrial DNA

Adam Eyre-Walker

That large populations harbor more genetic diversity than small ones holds true for nuclear genomes, but may not apply to mitochondrial DNA. If so, the use of mitochondrial DNA as a standard for genetic diversity may not be appropriate.

The author is at the National Evolutionary Synthesis Center, Durham, NC 27705, USA, and the Centre for the Study of Evolution, University of Sussex, Brighton BN1 9QG, UK. E-mail: a.c.eyre-walker{at}sussex.ac.uks

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
mtDNA Variation Predicts Population Size in Humans and Reveals a Major Southern Asian Chapter in Human Prehistory.
Q. D. Atkinson, R. D. Gray, and A. J. Drummond (2008)
Mol. Biol. Evol. 25, 468-474
   Abstract »    Full Text »    PDF »
Comment on "Population Size Does Not Influence Mitochondrial Genetic Diversity in Animals".
C. J. Mulligan, A. Kitchen, and M. M. Miyamoto (2006)
Science 314, 1390a
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)