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Science 28 April 2006:
Vol. 312. no. 5773, pp. 534 - 535
DOI: 10.1126/science.1127186
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Perspectives

BIOPHYSICS:
Lonely Voltage Sensor Seeks Protons for Permeation

Christopher Miller

The proton channel that ushers H ions across cell membranes to control cellular pH resembles an isolated voltage-sensing domain with no apparent pore.

The author is in the Department of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, MA 02454, USA. E-mail: cmiller{at}brandeis.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)