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Science 24 February 2006:
Vol. 311. no. 5764, pp. 1107 - 1109
DOI: 10.1126/science.1124662
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Perspectives

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MOLECULAR BIOLOGY:
Enhanced: "X"-Rated Chromosomal Rendezvous

Laura Carrel

Female mammals inactivate one of their two X chromosomes to ensure a dosage of genes equal to that of males who contain a single X. A brief union between the pair of X chromosomes may initiate this inactivation process.

The author is in the Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. E-mail: lcarrel{at}psu.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)