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Science 9 December 2005:
Vol. 310. no. 5754, pp. 1619 - 1620
DOI: 10.1126/science.1119727
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Books

EVOLUTION:
On the Origins of Novelty and Variation

Brian Charlesworth

The Plausibility of Life
Resolving Darwin's Dilemma
by Marc W. Kirschner and John C. Gerhart
Yale University Press, New Haven, CT, 2005. 330 pp. $30, £18.95. ISBN 0-300-10865-6.
The authors hold that the accumulation of small genetic mutations over time does not explain the variety and complexity of life. Instead, they propose "facilitated variation" to account for the conversion of random genetic change into complex innovations.

The reviewer is in the Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3JT, UK. E-mail: brian.charlesworth{at}ed.ac.uk

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Science. ISSN 0036-8075 (print), 1095-9203 (online)