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Science 25 November 2005:
Vol. 310. no. 5752, p. 1259
DOI: 10.1126/science.310.5752.1259a
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News of the Week

MEDICINE:
Cancer-Suppressing Enzyme Adds a Link to Type 2 Diabetes

Jean Marx

An enzyme known as LKB1, discovered about 7 years ago as the product of a tumor-suppressor gene, is now turning out to be a key regulator of the body's metabolic activities, including its handling of glucose--a discovery that connects LKB1 to type 2 diabetes and may explain its link to cancer. The work is published online this week by Science (www.sciencemag.org/cgi/content/abstract/1120781). (Read more.)

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Science. ISSN 0036-8075 (print), 1095-9203 (online)