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Science 28 October 2005:
Vol. 310. no. 5748, pp. 630 - 631
DOI: 10.1126/science.1120410
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Perspectives


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DEVELOPMENTAL BIOLOGY:
Enhanced: Less Steroids Make Bigger Flies

Kirst King-Jones and Carl S. Thummel

It has long been known that animal growth is achieved primarily during juvenile stages and terminates after sexual maturation. In their Perspective, King-Jones and Thummel discuss how the findings of Colombani et al. in this issue provide important new insights into how this coordination of growth and maturation is achieved through steroid and insulin signaling pathways.

The authors are in the Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. E-mail: kirst{at}genetics.utah.edu; carl.thummel{at}genetics.utah.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)