Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 29 July 2005:
Vol. 309. no. 5735, pp. 709 - 710
DOI: 10.1126/science.1116630
Prev | Table of Contents | Next

Perspectives

Also see the archival list of Science's Enhanced Perspectives and Policy Forums

MICROBIOLOGY:
Enhanced: Translocation of Anthrax Toxin: Lord of the Rings

Gunnar von Heijne[HN11]

Many microorganisms have evolved ingenious ways of shipping toxic proteins into target cells. In his Perspective, von Heijne discusses a study by Krantz et al. that reveals how anthrax toxin gets into a cell. A ring of aromatic amino acids in a pore formed by anthrax toxin helps unfold other anthrax toxin proteins and facilitate their translocation across the cell membrane.

The author is in the Department of Biochemistry and Biophysics, Stockholm University, SE-10691 Stockholm, Sweden. E-mail: gunnar{at}dbb.su.se

Read the Full Text

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)