VIROLOGY: Chemokine Gene Number Tied to HIV Susceptibility, But With a Twist

doi:10.1126/science.307.5706.23

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Science 7 January 2005:
Vol. 307. no. 5706, pp. 23 - 24
DOI: 10.1126/science.307.5706.23

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VIROLOGY:
Chemokine Gene Number Tied to HIV Susceptibility, But With a Twist

Jon Cohen

According to work described in the 6 January Science Express (www.sciencemag.org/cgi/content/abstract/1101160), the human genome is stockpiling extra copies of immune genes that influence a person's HIV susceptibility as well as the course of disease in infected people.

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In Science Magazine

RESEARCH ARTICLES The Influence of CCL3L1 Gene-Containing Segmental Duplications on HIV-1/AIDS Susceptibility: Enrique Gonzalez, Hemant Kulkarni, Hector Bolivar, Andrea Mangano, Racquel Sanchez, Gabriel Catano, Robert J. Nibbs, Barry I. Freedman, Marlon P. Quinones, Michael J. Bamshad, Krishna K. Murthy, Brad H. Rovin, William Bradley, Robert A. Clark, Stephanie A. Anderson, Robert J. O'Connell, Brian K. Agan, Seema S. Ahuja, Rosa Bologna, Luisa Sen, Matthew J. Dolan, and Sunil K. Ahuja (4 March 2005)
Science 307 (5714), 1434. [DOI: 10.1126/science.1101160]
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