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Science 26 November 2004:
Vol. 306. no. 5701, pp. 1453 - 1454
DOI: 10.1126/science.306.5701.1453a
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News of the Week

OBESITY RESEARCH:
New Data on Appetite-Suppressing Peptide Challenge Critics

Trisha Gura

In July, more than 40 scientists from 12 labs reported that they could not reproduce the appetite-squelching effects of peptide YY3-36 (PYY3-36) reported in 2002. This month, however, another group published data demonstrating that rats given intravenous infusions of PYY3-36 ate less than controls, in a dose-dependent fashion.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)