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Science 17 September 2004:
Vol. 305. no. 5691, pp. 1723 - 1724
DOI: 10.1126/science.1104244
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Perspectives

CELL BIOLOGY:
Double Membrane Fusion

Nikolaus Pfanner, Nils Wiedemann, Chris Meisinger

Mitochondria are highly dynamic organelles that undergo fusion and fission continuously as they partake in functions as varied as bioenergetics, apoptosis, and the differentiation of cells. In their Perspective, Pfanner et al. discuss development of a new in vitro assay that has enabled the intermediate steps in the fusion between two mitochondria to be analyzed in detail (Meeusen et al.).

The authors are in the Institut für Biochemie und Molekularbiologie, Universität Freiburg, D-79104 Freiburg, Germany. E-mail: nikolaus.pfanner{at}biochemie.uni-freiburg.de

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