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Science 11 June 2004:
Vol. 304. no. 5677, pp. 1610 - 1611
DOI: 10.1126/science.1099162
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Perspectives

DEVELOPMENTAL BIOLOGY:
Hox Genes in the Limb: A Play in Two Acts

Jacqueline Deschamps

The development of the tetrapod limb depends on complex cascades of gene expression. In her Perspective, Deschamps reports on a new study (Zákány et al.) that dissects the expression patterns and functions of the HoxD gene cluster during the early stages of limb bud development in the mouse.

The author is at the Hubrecht Laboratory, Uppsalalaan 8, 3584CT Utrecht, Netherlands. E-mail: jacqueli{at}niob.knaw.nl

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Science. ISSN 0036-8075 (print), 1095-9203 (online)