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Originally published in Science Express on 4 March 2004
Science 2 April 2004:
Vol. 304. no. 5667, pp. 58 - 60
DOI: 10.1126/science.1097146
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Perspectives

GENOMICS AND EVOLUTION:
Shotgun Sequencing in the Sea: A Blast from the Past?

Paul G. Falkowski and Colomban de Vargas

The enormous microbial diversity in the world's oceans is only starting to be explored. In their Perspective, Falkowski and de Vargas discuss a major effort using high-throughput DNA sequencing and computational genomics to identify all of the microbes in 1500 liters of surface seawater from the North Atlantic (Venter et al.).

P. G. Falkowski is with the Environmental Biophysics and Molecular Ecology Program and the Department of Geological Sciences. C. de Vargas is with Molecular Ecology and Evolution of Open Ocean Plankton, Institute of Marine and Coastal Science, Rutgers University, New Brunswick, NJ 08901, USA. E-mail: falko{at}imcs.rutgers.edu, vargas{at}imcs.rutgers.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Low Intraspecific Diversity in a Polynucleobacter Subcluster Population Numerically Dominating Bacterioplankton of a Freshwater Pond.
M. W. Hahn, M. Pockl, and Q. L. Wu (2005)
Appl. Envir. Microbiol. 71, 4539-4547
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Exploring the diversity of complex metabolic networks.
V. Hatzimanikatis, C. Li, J. A. Ionita, C. S. Henry, M. D. Jankowski, and L. J. Broadbelt (2005)
Bioinformatics 21, 1603-1609
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Darwinian adaptation of proteorhodopsin to different light intensities in the marine environment.
J. P. Bielawski, K. A. Dunn, G. Sabehi, and O. Beja (2004)
PNAS 101, 14824-14829
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